Airplane!

Paramount Pictures/Courtesy Neal Peters Collection

Directors: Jim Abrahams, David Zucker, Jerry Zucker

Cast: Robert Hays, Julie Hagerty, Leslie Nielsen 

Domestic lifetime gross (adjusted for inflation 2014): $246,948,000

Famous quote: "There's no reason to become alarmed, and we hope you'll enjoy the rest of your flight. By the way, is there anyone on board who knows how to fly a plane?" — Elaine Dickinson

The film that forever changed the way people think about Robert Stack, Lloyd Bridges, Peter Graves, Barbara Billingsley and especially Nielsen.